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Publications :

Epigenetics of Regeneration and Cancer (E-ReCa)

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Three classes of epigenomic regulators converge to hyperactivate the essential maternal gene deadhead within a heterochromatin mini-domain

Torres-Campana D, Horard B, Denaud S, Benoit G, Loppin B, Orsi GA.

PLoS Genet 2022 Jan 4;18(1):e1009615. doi: 10.1371/journal.pgen.1009615

The Lid/KDM5 histone demethylase complex activates a critical effector of the oocyte-to-zygote transition

Torres-Campana D#, Kimura S#, Orsi GA, Horard B, Benoit G, Loppin B.

PLoS Genet 2020 Mar 5;16(3):e1008543. doi:10.1371/journal.pgen.1008543

Two HIRA- dependent pathways mediate H3.3 de novo deposition and recycling during transcription

Torné J, Ray-Gallet D, Boyarchuk E, Garnier M, Le Baccon P, Coulon A, Orsi GA*, Almouzni…

Nat Struct Mol Biol. 2020 Nov;27(11):1057-1068. doi: 10.1038/s41594-020-0492-7

High-resolution visualization of H3 variants during replication reveals their controlled recycling

Clément C, Orsi GA, Gatto A, Boyarchuk E, Forest A, Hajj B, Miné-Hattab J, Garnier M,…

Nat Commun 2018 Aug 9;9(1):3181. doi:10.1038/s41467-018-05697-1

Imaging Newly Synthesized and Old Histone Variant Dynamics Dependent on Chaperones Using the SNAP-Tag System

Torné J, Orsi GA, Ray-Gallet D, Almouzni G.

Methods Mol Biol 2018 1832:207-221. doi: 10.1007/978-1-4939-8663-7_11. PMID: 30073529.

Mapping regulatory factors by immunoprecipitation from native chromatin

Orsi GA#, Kasinathan S#, Zentner GE, Henikoff S, Ahmad K.

Curr Protoc Mol Biol 2015 Apr 1;110:21.31.1-21.31.25. doi: 10.1002/0471142727.mb2131s110.

High-resolution mapping defines the cooperative architecture of Polycombresponse elements

Orsi GA, Kasinathan S, Hughes KT, Saminadin-Peter S, Henikoff S, Ahmad K.

Genome Res 2014 May;24(5):809-20. doi:10.1101/gr.163642.113

High-resolution mapping of transcription factor binding sites on native chromatin

Kasinathan S, Orsi GA, Zentner GE, Ahmad K, Henikoff S.

Nat Methods 2014 Feb;11(2):203-9. doi: 10.1038/nmeth.2766

Drosophila Yemanuclein and HIRA cooperate for de novo assembly of H3.3-containing nucleosomes in the male pronucleus

Orsi GA, Algazeery A, Meyer RE, Capri M, Sapey-Triomphe LM, Horard B, Gruffat H, Couble…

PLoS Genet. 2013 9(2):e1003285. doi: 10.1371/journal.pgen.1003285.

Nucleosome-depleted chromatin gaps recruit assembly factors for the H3.3 histone variant.

Schneiderman JI#, Orsi GA#, Hughes KT, Loppin B, Ahmad K.

Proc Natl Acad Sci U S A 2012 Nov 27;109(48):19721-6. doi: 10.1073/pnas.1206629109

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