Publications :

Aberrant activation of five embryonic stem cell-specific genes robustly predicts a high risk of relapse in breast cancers

Jacquet E, Chuffart F, Vitte AL, Nika E, Mousseau M, Khochbin S, Rousseaux S, Bourova-Flin…

BMC Genomics 2023 Aug 17;24(1):463. doi: 10.1186/s12864-023-09571-3. PMID: 37592220; PMCID:PMC10436393

High levels of histone H3 K27 acetylation and tri-methylation are associated with shorter survival in oral squamous cell carcinoma patients

Shahhosseini A, Bourova-Flin E, Derakhshan S, Aminishakib P, Goudarzi A.

Biomedicine (Taipei) 2023 Mar 1;13(1):22-38. doi: 10.37796/2211-8039.1391. PMID: 37168723; PMCID:PMC10166250

Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia

Xi M, Guo S, Bayin C, Peng L, Chuffart F, Bourova-Flin E, Rousseaux S, Khochbin…

Front Med 2022 Jun;16(3):442-458. doi:10.1007/s11684-021-0877-y. Epub 2021 Oct 20. PMID: 34669156.

Ectopic expression of a combination of 5 genes detects high risk forms of T-cell acute lymphoblastic leukemia

Peng LJ, Zhou YB, Geng M, Bourova-Flin E, Chuffart F, Zhang WN, Wang T, Gao…

BMC Genomics 2022 Jun 24;23(1):467. doi:10.1186/s12864-022-08688-1. PMID: 35751016; PMCID: PMC9233359.

NUT Is a Driver of p300-Mediated Histone Hyperacetylation: From Spermatogenesis to Cancer

Rousseaux S, Reynoird N, Khochbin S.

Cancers (Basel) 2022 Apr 29;14(9):2234. doi: 10.3390/cancers14092234. PMID: 35565363; PMCID:PMC9103113

Optimized outcome prediction of oncogenetic mutations in non-early T-cell precursor acute lymphoblastic leukemia

Peng LJ, Wang SS, Guo SS, Zhang JJ, Liu YF, Rousseaux S, Khochbin S, Chen…

Immunobiology 2022 May;227(3):152205. doi: 10.1016/j.imbio.2022.152205. Epub 2022 Mar 8. PMID:35279479

The combined detection of Amphiregulin, Cyclin A1 and DDX20/Gemin3 expression predicts aggressive forms of oral squamous cell carcinoma

Bourova-Flin E, Derakhshan S, Goudarzi A, Wang T, Vitte AL, Chuffart F, Khochbin S, Rousseaux…

Br J Cancer 2021 Oct;125(8):1122-1134. doi:10.1038/s41416-021-01491-x. Epub 2021 Jul 21. PMID: 34290392; PMCID: PMC8505643.

EDEN Mother-Child Cohort Study Group. Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions

Rousseaux S, Seyve E, Chuffart F, Bourova-Flin E, Benmerad M, Charles MA, Forhan A, Heude…

BMC Med 2020 Oct 7;18(1):306. doi:10.1186/s12916-020-01736-1. PMID: 33023569; PMCID: PMC7542140.

Histone variants: critical determinants in tumour heterogeneity

Wang T, Chuffart F, Bourova-Flin E, Wang J, Mi J, Rousseaux S, Khochbin S.

Front Med 2019 Jun;13(3):289-297. doi: 10.1007/s11684-018-0667-3. Epub 2019 Jun 11. PMID:30280307

Regulators of the male epigenome: Markers and potential targets for anticancer therapy

Rousseaux S, Bourova-Flin E, Chuffart F, Khochbin S.

Bull Cancer 2019 Oct;106(10):836-838. French. doi:10.1016/j.bulcan.2019.08.003. Epub 2019 Aug 23. PMID: 31451187.

The Role of Bromodomain Testis-Specific Factor, BRDT, in Cancer: A Biomarker and A Possible Therapeutic Target

Bourova-Flin E, Chuffart F, Rousseaux S, Khochbin S.

Cell J 2017 Spring;19(Suppl 1):1-8. doi: 10.22074/cellj.2017.5060. Epub 2017 May 17. PMID: 28580303; PMCID: PMC5448322.

A six gene expression signature defines aggressive subtypes and predicts outcome in childhood and adult acute lymphoblastic leukemia.

Wang J, Mi JQ, Debernardi A, Vitte AL, Emadali A, Meyer JA, Charmpi K, Ycart…

Oncotarget 2015 Jun 30;6(18):16527-42. doi:10.18632/oncotarget.4113. PMID: 26001296; PMCID: PMC4599287