Publications :

In vitro production of cat-restricted Toxoplasma pre-sexual stages

Ana Vera Antunes, Martina Shahinas, Christopher Swale, Dayana C. Farhat, Chandra Ramakrishnan, Christophe Bruley, Dominique…

Nature 2024 These authors contributed equally: Ana Vera Antunes, Martina Shahinas, Christopher Swale

Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a kinase critical for splicing.

Swale C@, Bellini V, Matthew W. Bowler, Nardella Flore, Marie-Pierre Brenier-Pinchart, Dominique Cannella, Lucid Belmudes,…

Science Translational Medicine 2022 These authors contributed equally: Christopher Swale, Bellini Valeria

The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages.

Ten Hoeve AL, Braun L, Rodriguez ME, Olivera GC, Bougdour A, Belmudes L, Couté Y,…

Cell Host Microbe 2022 Oct 20;S1931-3128(22)00512-1.

A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection

Dard C, Swale C, Brenier-Pinchart MP, Farhat DC, Bellini V, Robert MG, Cannella D, Pelloux…

BMC Biol. 2021 Feb 9;19(1):25

A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental genes partitioning in Toxoplasma

Farhat DC, Bowler M, Communie G, Pontier D, Belmudes L, Mas C, Coute Y, Bougdour…

Elife 2021 Jul 15;10:e68312

A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment

Farhat DC, Swale C, Dard C, Cannella D, Ortet P, Barakat M, Sindikubwabo F, Belmudes…

Nature Microbiology 2020 Feb 24. doi: 10.1038/s41564-020-0674-4

Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection.

Swale C, Bougdour A, Gnahoui-David A, Tottey J, Georgeault S, *Laurent F, *†Palencia A, *†Hakimi…

Science Translational Medicine 2019 Nov 6;11(517). pii:eaax7161

The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-kB signalling via EZH2

Braun L, Brenier-Pinchart MP, Hammoudi PM, Cannella D, Kieffer-Jaquinod S, Vollaire J, Josserand V, Touquet…

Nature Microbiology 2019 Jul;4(7):1208-1220.

Characterization of a Toxoplasma effector uncovers an alternative GSK3/b-catenin-regulatory pathway of inflammation.

He H, Brenier-pinchart MP, Braun L, Kraut A, Touquet B, Coute Y, Tardieux I, Hakimi…

Elife 2018 Oct 15;7. pii: e39887

Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites

Sindikubwabo F, Ding S, Hussain T, Ortet P, Barakat M, Baumgarten S, Cannella D, Palencia…

Elife 2017 Nov 4;6. pii: e29391.

Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

*Palencia A, *Bougdour A, Brenier-pinchart MP, Touquet B, Bertini RL, Vollaire J, Josserand V, Eason…

EMBO Mol Med 2017 Mar;9(3):385-394.