A P5-ATPase, TgFLP12, diverging from plant chloroplast lipid transporters mediates apicoplast fatty export in Toxoplasma.
Arnold CS, Alazzi AM, Shunmugam S, Janouškovec J, Berry L, Charital S, Gautier T, Duley…
Nature Communications 2025 Lipids are crucial for Apicomplexa survival in their human hosts. They can acquire lipids from the host cell and/or make its own in a relict non-photosynthetic and essential plastid, the apicoplast, which represents a plant-like Achilles’ Heel for the par