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Les publications :

Thérapie ciblée, diagnostic précoce et imagerie du cancer

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Biological Templates for Gold Nanocluster Assembly: Design and Biomedical Applications

Z. Ayed, A. Alhalabi, D. Gasparutto, X. Le Guével.

Aggregate 2026

ENDOSWIR clinical proof of concept: a reflectance-based multispectral imaging device for head and neck cancer detection

C. Fabre, M. Henry, N. Dutrieux, H. Gil, A. Koenig, P. Abraham, P. Le Coupanec,…

Biomed Opt Express 2026

Influence of PEGylation and Surface Charge on Biodistribution of Shortwave Infrared Emitting Nanoparticles for In Vivo Bioimaging

L. Haye*, M. Henry, V. Josserand, F. Abdul Rezak, A. Olave Velasco, S. Erbek, V.…

ACS Applied Nano Materials 2026

Programming the Optoelectronic Properties of Atomically Precise Gold Nanoclusters Using the Conformational Landscape of Intrinsically Disordered Proteins

S. Rodriguez, S. Kumanski, Z. Ayed, A. Fournet, C. Bouanchaud, A. Sagar, F. Allemand, V.…

Chemistry 2026

Radiodynamic Properties of Liposomes Encapsulating a Bi Triple-Decker Phthalocyanine

S. Leo, E. Murillo Vilella, L. Contini, F. Grepioni, R. Haudecoeur, P. Lanoë, M. Kadri,…

ACS Appl Mater Interfaces 2026

Bioorthogonal conjugation of NIR luminescent gold nanoclusters with multifunctional polymers: insights into binding efficiency, kinetics, and optical properties.

F. Abdul Rezak, P. Catal, L. Mantout, F. Da Cruz, D. Boturyn, J. Coll, A.…

Nanoscale Adv 2025

Combined physical and biological contributions to radiotherapy enhancement by Lu-based nanoscintillators in pancreatic cancer models.

Stelse-Masson, S., Lytvynenko, X., Bedregal-Portugal, K., Aubrun, C., Lavaud, M., Kadri, M., Jacquet, T., Moriscot,…

Nanotheranostics 2025 Methods: In this paper, we study the ability of Lu 3 Al 5 O 12: Pr@ SiO 2, a lutetium-based nanoscintillator, to exert a radiation dose-enhancement effect in two human pancreatic cancer cell models, namely PANC-1 and MIA PaCa-2. Results: Lu 3 Al 5 O 12:

In vivo vectorization and delivery systems for gene therapies and RNA-based therapeutics in oncology

Schock Vaiani, J. Broekgaarden, M. Coll, J. L. Sancey, L. Busser, B.

Nanoscale 2025 Gene and RNA-based therapeutics represent a promising frontier in oncology, enabling targeted modulation of tumor-associated genes and proteins. This review explores the latest advances in payload vectorization and delivery systems developed for in vivo c

Monomer Versus Dimer of Cationic Ir(III) Complexes for Photodynamic Therapy by Two-Photon Activation: A Comparative Study.

Barta, A., Vanwonterghem, L., Lavaud, M., Molton, F., Micouin, G., Bulin, A. L., Banyasz, A.,…

ACS Appl Bio Mater 2025 Iridium(III) complexes have been recognized as promising candidates for two-photon sensitized photodynamic therapy (PDT). In this context, we report on the study of two complexes: a monomer (IrL(1)) and a dimer (Ir(2)L(2)). Both complexes possess 2-phenyl

Multifunctional micro/nano-textured titanium with bactericidal, osteogenic, angiogenic and anti-inflammatory properties: Insights from in vitro and in vivo studies

Ziegelmeyer, T. Martins de Sousa, K. Liao, T. Y. Lartizien, R. Delay, A. Vollaire, J.…

Mater Today Bio 2025 Titanium (Ti) is widely used as an implantable material for bone repair in orthopedics and dentistry. However, Ti implants are vulnerable to bacterial infections, which can compromise patient recovery and lead to implant failure. While a controlled inflam

Photodynamic drug delivery for cancer therapy: Designing liposomes for light-controlled release and enhanced drug efficacy.

T. Le Clainche, A. Abdelhamid, N. Carigga Gutierrez, M. Jourdain, S. Leo, L. Sancey, A.…

Eur J Pharm Sci 2025 213 107221. 2025 Photodynamics involves the use of photocatalytic compounds that, upon excitation with light, produce reactive oxygen species and have seen widespread applications in the treatment of cancer in the form of photodynamic therapy. Within the field of drug del

Self-Assembled Peptide-Gold Nanoclusters with SiRNA Targeting Telomeric Response to Enhance Radiosensitivity in Lung Cancer Cells

Moro, S., Omrani, M., Erbek, S., Jourdan, M., Vandekerckhove, C. I., Nogier, C., Vanwonterghem, L.,…

Small Science 2025 Lung cancer cells resistant to radiotherapy present a significant clinical challenge. Stable telomeric structures, maintained by the TRF2 protein, play a critical role in protecting cells from ionizing radiation. Reduced TRF2 expression increases DNA dama

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