Les publications :

Altered splicing of ATG16-L1 mediates acquired resistance to Tyrosine kinase inhibitors of EGFR by blocking autophagy in non-small cell lung cancer

Hatat A.S., Benoit-Pilven C., Pucciarelli A., De Fraipont F., Lamothe L., Perron P., Rey A.,…

Mol Oncol 2022 16 :3490-3508 doi: 10.1002/1878-0261.13229

FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells

Jia T, Jacquet T, Dalonneau F, Coudert P, Vaganay E, Exbrayat-Héritier C, Vollaire J, Josserand…

BMC Biology 2021 19(1):173. doi: 10.1186/s12915-021-01103-3

VEGF165b, a splice variant of VEGF-A, promotes lung tumor progression and escape from anti-angiogenic therapies through a β1 integrin/VEGFR autocrine loop

Boudria A, Abou Faycal C, Jia T, Gout S, Keramidas M, Didier C, Lemaitre N,…

Oncogene 2019 38(7):1050-1066 doi: 10.1038/s41388-018-0486-7

Heteromultivalent targeting of integrin avb3 and neuropilin 1 promotes cell survival via the activation of the IGF-1/insulin receptors

Jia T, Choi J, Ciccione J, Henry M, Mehdi A, Martinez J, Eymin B, Subra…

Biomaterials 2018 155:64-79 doi: 10.1016/j.biomaterials.2017.10.042

Nuclear translocation of IGF-1R by intracellular amphiregulin contributes to the resistance of lung tumor cells to EGFR-TKI

Guerard M, Robin T, Perron P, Hatat A.S, David-Boudet L, Busser B, Coll J.L, Lantuejoul…

Cancer Letters 2018 420:146-155 doi: 10.1016/j.canlet.2018.01.080

The sVEGFR1-il3 splice variant regulates a beta1 integrin/VEGFR autocrine loop involved in the progression and the responce to anti-angiogenic therapies of squamous cell lung carcinoma

Abou Faycal C, Brambilla E, Agorreta J, Lepeltier N, Jacquet T, Lemaitre N, Emadali A,…

British Journal of Cancer 2018 118 :1596-1608 doi: 10.1038/s41416-018-0128-4. 

Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival

Dayde D, Guerard M, Perron P, Hatat A.S, Barrial C, Eymin B and Gazzeri S.

Oncogene 2016 35(30):3986-94. doi: 10.1038/onc.2015.480.

p14ARF inhibits the growth of lung adenocarcinoma cells harboring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway

Ozenne P, Dayde D, Brambilla E, Eymin B and Gazzeri S.

Oncogene 2013 32(8):1050-8 doi: 10.1038/onc.2012.107. 

Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin

Edmond V, Moysan E, Khochbin S, Matthias P, Brambilla C, Brambilla E, Gazzeri S and…

EMBO J 2011 30(3):510-23 doi: 10.1038/emboj.2010.333

E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35

Merdzhanova G, Edmond V, De Seranno S, Van Den Broeck A, Corcos L, Brambilla C,…

Cell Death Diff 2008 15 :1815-1823 doi: 10.1038/cdd.2008.135.