Les publications :

Bipartite binding of the intrinsically disordered scaffold protein JIP1 to the kinase JNK1.

Orand, T., Delaforge, E., Lee, A., Kragelj, J., Davis, RJ., Palencia, A.*, Jensen, MR.*

Proceedings of the National Academy of Sciences of USA. 2025

Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis.

Casanova, AG., Roth, GS., Hausmann, S., Lu, X., Bischoff, LJM., Froeliger, EM., ... Rousseaux, S.,…

Cell Discovery 2024 10(1):12. doi: 10.1038/s41421-023-00644-x.

Phage display identification of high-affinity ligands for human TSG101-UEV: A structural and thermodynamic study of PTAP recognition.

Murciano-Calles, J., Rodríguez-Martínez, A., Palencia, A., Andújar-Sánchez, M., Iglesias-Bexiga, M., Corbi-Verge, C., Buzón, P., Ruiz-Sanz,…

Int J Biol Macromol. 2024 274(1):133233, 10.1016.

Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1

Mariño Pérez, L., Ielasi, FS., Lee, A., Delaforge, E., Juyoux, P., Tengo, M., Davis, RJ.,…

Structure 2024 S0969-2126(24)00228-4. doi: 10.1016/j.str.2024.06.010

Targeting a microbiota Wolbachian aminoacyl-tRNA synthetase to block its pathogenic host.

Hoffmann, G., Lukarska, M., Clare, RH., Masters, EKG., Johnston, KL., Ford, L., Turner, JD., Ward,…

Science Advances 2024 10(28):eado1453. doi: 10.1126/sciadv.ado1453.

Adenosine Dependent Activation Mechanism of Prodrugs Targeting an Aminoacyl-tRNA Synthetase

Hoffmann, G., Le Gorrec, M., Mestdach, E., Cusack, S., Salmon, L., *Jensen, MR. & *Palencia,…

Journal of The American Chemical Society 2023 145(2), 800-810. *Corresponding authors

Binding stoichiometry and structural model of the HIV-1 Rev/importin β complex.

Spittler, D., Indorato, RL., Boeri-Erba, E., Delaforge, E., Signor, L., Harris, SJ., Garcia-Saez, I., Palencia,…

Life Science Alliance 2022 5(10):e202201431. doi: 10.26508/lsa.202201431.

Human Histone pre-mRNA Assembles Histone- or Canonical-mRNA Processing Complexes by Overlapping 3’-End Sequence Elements

Ielasi, F.S., Ternifi, S., Fontaine, E., Iuso, D., Couté, Y. & *Palencia A.

Nucleic Acids Research 2022 28; 50 (21):12425-12443

Structural basis of sodium-dependent bile salt uptake into the liver.

Goutam, K., Ielasi, FS., Pardon, E., Steyaert, J., Reyes N.

Nature 2022 606(7916):1015-1020. doi: 10.1038/s41586-022-04723-z

Visualizing protein breathing motions associated with aromatic ring flipping

Mariño Perez, L., Ielasi, FS., Bessa, LM., Maurin, D., Kragelj, J., Salvi, N., Bouvignies, G., *Palencia,…

Nature 2022 602, 695-700. *Corresponding authors

Enthalpy–entropy compensation in the promiscuous interaction of an intrinsically disordered protein with homologous protein partners.

Kragelj, J., Orand, T., Delaforge, E., Tengo, L., Blackledge, M., Palencia, A. & Jensen, MR.

Biomolecules 2021 11(8):1204. doi: 10.3390/biom11081204.

Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.

Liu, RJ., Long, T., Li, H., Zhao, J., Li, J., Wang, M., Palencia, A., Lin,…

Nucleic Acids Research 2020  48(9):4946-4959. doi: 10.1093/nar/gkaa189.