Les publications :

A comprehensive study of the sperm head defects in MMAF condition and their impact on embryo development in mice

Jana Muroňová, Emeline Lambert, Chanyuth Thamwan, Zeina Wehbe, Magali Court, Geneviève Chevalier, Jessica Escoffier, Zine-Eddine…

Molecular Humain Reproduction 2025

A recurrent loss-of-function variant in DRC1 causes non-syndromic severe asthenozoospermia with favorable intracytoplasmic sperm injection and pregnancy outcomes

Célia Tebbakh, Anne-Laure Barbotin, Guillaume Martinez, Angèle Boursier, Zeina Wehbe, Asma Hammouda, Nicolas Thierry-Mieg, Christophe…

Andrology 2025

Deciphering the Contribution of Circular RNAs to Age-Related Decline in Sertoli Cell Survivor.

Manfrevola F, Mosca N, Mele VG, Chioccarelli T, Martinez G, Coutton C, Mattia M, Pezzullo…

Aging Cell 2025

Homozygous deleterious variants in MYCBPAP induce asthenoteratozoospermia involving abnormal acrosome biogenesis, manchette structure and sperm tail assembly in humans and mice

Yiling Zhou, Chaofeng Tu, Charles Coutton, Jianan Tang, Shixiong Tian, Shuyan Tang, Guillaume Martinez, Dapeng…

Science China Life Science 2025

Phenotypic continuum and poor intracytoplasmic sperm injection intracytoplasmic sperm injection prognosis in patients harboring HENMT1 variants

Zeina Wehbe, Anne-Laure Barbotin, Angèle Boursier, Caroline Cazin, Jean-Pascal Hograindleur, Marie Bidart, Emeline Fontaine, Pauline…

Andrology 2025

Sperm fertility in mice with Oligo-astheno-teratozoospermia restored by in vivo injection and electroporation of naked mRNA.

Vilpreux C, Martinez G, Court M, Appaix F, Duteyrat JL, Henry M, Vollaire J, Ayad…

eLife 2025

Whole genome sequencing identifies a homozygous splicing variant in TDRKH segregating with non-obstructive azoospermia in an Iranian family

Amir Amiri-Yekta, Sharanya Sen, Florence Hazane-Puch, Célia Tebbakh, Nathalie Roux-Buisson, Caroline Cazin, Nicolas Thierry-Mieg, Ahmed…

Clinical Genetics 2025

A splice donor variant of GAS8 induces structural disorganization of the axoneme in sperm flagella and leads to nonsyndromic male infertility.

Kherraf ZE, Barbotin AL, Martinez G, Mazet A, Cazin C, Coutton C, Arnoult C, Thierry-Mieg…

Clin Genet. 2024

BRCA1 Intragenic Duplication Combined with a Likely Pathogenic TP53 Variant in a Patient with Triple-Negative Breast Cancer: Clinical Risk and Management.

Ea V, Berthozat C, Dreyfus H, Legrand C, Rousselet E, Peysselon M, Baudet L, Martinez…

Int J Mol Sci. 2024

CCDC65, encoding a component of the axonemal Nexin-Dynein regulatory complex, is required for sperm flagellum structure in humans.

Jreijiri F, Cavarocchi E, Amiri-Yekta A, Cazin C, Hosseini SH, El Khouri E, Patrat C,…

Clin Genet 2024

CNN-based approach for 3D artifact correction of intensity diffraction tomography images.

Pierré W, Briard M, Godefroy G, Desissaire S, Dhellemmes M, Llano ED, Loeuillet C, Ray…

Opt Express 2024

Constitutive Androstane Receptor Regulates Germ Cell Homeostasis, Sperm Quality, and Male Fertility via Akt-Foxo1 Pathway.

Monrose M, Holota H, Martinez G, Damon-Soubeyrand C, Thirouard L, Martinot E, Battistelli E, de…

Adv Sci 2024