Les publications :

Understanding the genetics of human infertility.

Sang Q, Ray PF, Wang L.

Science 2023

3D time-lapse imaging of a mouse embryo using intensity diffraction tomography embedded inside a deep learning framework

Pierré W, Hervé L, Paviolo C, Mandula O, Remondiere V, Morales S, Grudinin S, Ray…

Appl Opt 2022

From azoospermia to macrozoospermia, a phenotypic continuum due to mutations in the ZMYND15 gene.

Kherraf ZE, Cazin C, Bouker A, Fourati Ben Mustapha S, Hennebicq S, Septier A, Coutton…

Am J Hum Genet 2022

Homozygous mutations in CCDC34 cause male infertility with oligoasthenoteratozoospermia in humans and mice.

Cong J, Wang X, Amiri-Yekta A, Wang L, Kherraf ZE, Liu C, Cazin C, Tang…

J Med Genet. 2022

Oligogenic heterozygous inheritance of sperm abnormalities in mouse

Martinez G, Coutton C, Loeuillet C, Cazin C, Muroňová J, Boguenet M, Lambert E, Dhellemmes…

Elife 2022 Apr 22;11:e75373. doi: 10.7554/eLife.75373.

Treatment of Mouse Sperm with a Non-Catalytic Mutant of PLA2G10 Reveals That PLA2G10 Improves In Vitro Fertilization through Both Its Enzymatic Activity and as Ligand of PLA2R1.

Abi Nahed R, Dhellemmes M, Payré C, Le Blévec E, Perrier JP, Hennebicq S, Escoffier…

Int J Mol Sci. 2022

When idiopathic male infertility is rooted in maternal malnutrition during the perinatal period in mice.

Muranishi Y, Parry L, Vachette-Dit-Martin M, Saez F, Coudy-Gandilhon C, Sauvanet P, Volle DH, Tournayre…

Biol Reprod 2022

Whole-exome sequencing improves the diagnosis and care of men with non-obstructive azoospermia

Kherraf ZE, Cazin C, Bouker A, Fourati Ben Mustapha S, Hennebicq S, Septier A, Coutton…

Am J Hum Genet 2022 Mar 3;109(3):508-517. doi: 10.1016/j.ajhg.2022.01.011. Epub 2022 Feb 15

A missense mutation in IFT74, encoding for an essential component for intraflagellar transport of Tubulin, causes asthenozoospermia and male infertility without clinical signs of Bardet-Biedl syndrome.

Lorès P, Kherraf ZE, Amiri-Yekta A, Whitfield M, Daneshipour A, Stouvenel L, Cazin C, Cavarocchi…

Hum Genet. 2021

A recurrent ZP1 variant is responsible for oocyte maturation defect with degenerated oocytes in infertile females

Corinne Loeuillet, Magali Dhellemmes, Caroline Cazin, Zine-Eddine Kherraf, Selima Fourati Ben Mustapha, Raoudha Zouari, Nicolas…

Clinical Genetics 2021

AFU and SALF recommendations for the evaluation of male infertility.

Huyghe E, Boitrelle F, Methorst C, Mieusset R, Ray PF, Akakpo W, Koscinski I, Chalas…

Prog Urol. 2021

Ankrd31 in Sperm and Epididymal Integrity.

Manfrevola F, Martinez G, Coutton C, Rocco D, Reynaud K, Le Vern Y, Froment P,…

Front Cell Dev Biol 2021