Les publications

A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment

Farhat DC, Swale C, Dard C, Cannella D, Ortet P, Barakat M, Sindikubwabo F, Belmudes…

Nature Microbiology 2020 Feb 24. doi: 10.1038/s41564-020-0674-4

An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial

Charles J, Chaperot L, Hannani D, Bruder Costa J, Templier I, Trabelsi S, Gil H,…

Oncoimmunology 2020 Apr 12;9(1):1738812. doi: 10.1080/2162402X.2020.1738812. PMID: 32313721; PMCID: PMC7153838

Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility.

Liu C, Miyata H, Gao Y, Sha Y, Tang S, Xu Z, Whitfield M, Patrat…

Am J Hum Genet 2020

Complexity and diversity of sperm physiology.

Arnoult C

Mol Cell Endocrinol 2020

Coupling Polar Adhesion with Traction, Spring, and Torque Forces Allows High-Speed Helical Migration of the Protozoan Parasite Toxoplasma

Pavlou G, Touquet B, Vigetti L, Renesto P, Bougdour A, Debarre D, Balland M, Tardieux…

ACS Nano 2020 Jun 23;14(6):7121-7139

De novo SMARCA2 variants clustered outside the helicase domain cause a new recognizable syndrome with intellectual disability and blepharophimosis distinct from Nicolaides-Baraitser syndrome

Cappuccio G, et al.

Genet Med . 2020 Nov;22(11):1838-1850. doi: 10.1038/s41436-020-0898-y. Epub 2020 Jul 22.

Deslorelin acetate implant induces transient sterility and behavior changes in male olive baboon (Papio anubis): A case study

Martinez G, Lacoste R, Dumasy M, Garbit S, Brouillet S, Coutton C, Arnoult C, Druelle…

J Med Primatol 2020

Diversity of RNA-Binding Proteins Modulating Post-Transcriptional Regulation of Protein Expression in the Maturing Mammalian Oocyte.

Christou-Kent M, Dhellemmes M, Lambert E, Ray PF, Arnoult C.

Cells. 2020

Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling.

Amiar S, Katris NJ, Berry L, Dass S, Duley S, Arnold CS, Shears MJ, Brunet…

Cell Reports 2020 CNRS National Press release: https://www.insb.cnrs.fr/fr/cnrsinfo/comment-le-parasite-sadapte-la-nutrition-de-son-hote

EDEN Mother-Child Cohort Study Group. Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions

Rousseaux S, Seyve E, Chuffart F, Bourova-Flin E, Benmerad M, Charles MA, Forhan A, Heude…

BMC Med 2020 Oct 7;18(1):306. doi:10.1186/s12916-020-01736-1. PMID: 33023569; PMCID: PMC7542140.

Effects of timing of artificial insemination and treatment of semen with a Slo3 potassium channel blocker on fertility of dairy heifers subjected to the 5-day CIDR-Synch protocol.

Figueiredo CC, Bisinotto DZ, Chebel RC, Thatcher WW, Arnoult C, Faust MA, Schmitt E, Bisinotto…

J Dairy Sci 2020

Fast and ergonomic extraction of adherent mammalian cells for NMR-based metabolomics studies

Mili M.; Panthu B, Madec A.-M, Berger M.-A, Rautureau G. J. P, Elena-Herrmann B

Anal. Bioanal. Chem. 2020 412, 5453. doi: 10.1007/s00216-020-02764-9.

Genetics of teratozoospermia: Back to the head.

Beurois J, Cazin C, Kherraf ZE, Martinez G, Celse T, Touré A, Arnoult C, Ray…

Best Pract Res Clin Endocrinol Metab 2020

High-Resolution Shortwave Infrared Imaging of Vascular Disorders Using Gold Nanocluster

Yu, Z., Musnier, B., Wegner, K. D., Henry, M., Chovelon, B., Desroches-Castan, A., Fertin, A.,…

ACS Nano 2020 14, 4973-4981

Homozygous mutations in SPEF2 induce multiple morphological abnormalities of the sperm flagella and male infertility.

Liu C, Lv M, He X, Zhu Y, Amiri-Yekta A, Li W, Wu H, Kherraf…

J Med Genet 2020

Identification, Characterization and Synthesis of Walterospermin, a Sperm Motility Activator from the Egyptian Black Snake Walterinnesia aegyptia Venom.

Abd El-Aziz TM, Jaquillard L, Bourgoin-Voillard S, Martinez G, Triquigneaux M, Zoukimian C, Combemale S,…

Int J Mol Sc 2020

Live imaging of single platelets at work.

Sadoul K, Lafanechère L, Grichine A.

Platelets. 2020 Jul 3;31(5):551-558. doi: 10.1080/09537104.2019.1708886. Epub 2019 Dec 27. PMID: 31880193. 2020

Lysine Methyltransferases Signaling: Histones are Just the Tip of the Iceberg

Lukinović V, Casanova AG, Roth GS, Chuffart F, Reynoird N.

Curr Protein Pept Sci 2020 21(7):655-674. doi: 10.2174/1871527319666200102101608. PMID: 31894745

Measuring cell displacements in opaque tissues: dynamic light scattering in the multiple scattering regime

Brunel B, Levy V, Millet A, Dolega ME, Delon A, Pierrat R, Cappello G.

Biomed Opt Express 2020 Mar 31;11(4):2277-2297. doi: 10.1364/BOE.388360

Mechano-Bactericidal Titanium Surfaces for Bone Tissue Engineering

Clainche, T. L., Linklater, D., Wong, S., Le, P., Juodkazis, S., Guevel, X. L., Coll,…

ACS Appl Mater Interfaces 2020 12, 48272-48283

Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.

Liu, RJ., Long, T., Li, H., Zhao, J., Li, J., Wang, M., Palencia, A., Lin,…

Nucleic Acids Research 2020  48(9):4946-4959. doi: 10.1093/nar/gkaa189.

Multi-platform NMR Study of Pluripotent Stem Cells Unveils Complementary Metabolic Signatures towards Differentiation

Elena-Herrmann B, Montellier E, Fages A, Bruck-Haimson R, Moussaieff A

Sci. Rep 2020 10, 1622. doi: 10.1038/s41598-020-58377-w

Pantoprazole, a proton-pump inhibitor, impairs human sperm motility and capacitation in vitro.

10. Escoffier, J., Arnaud, B., Kaba, M., Hograindleur, J., Le Blévec, E., Martinez, G., Stévant,…

Andrology 2020

Paternal epigenetics: Mammalian sperm provide much more than DNA at fertilization

Le Blévec E, Muroňová J, Ray PF, Arnoult C

Mol Cell Endocrinol 2020

Piezoelectric Actuated Glass Plate for Liquid Density and Viscosity Measurement

Neff B, Casset F, Millet A, Agache V, Colin M.

Micromachines (Basel) 2020 Mar 27;11(4):348. doi: 10.3390/mi11040348.

Prebiotic role of softwood hemicellulose in healthy mice model

Deloule V, Boisset C, Hannani D, Suau A, Le Gouellec A, Chroboczek J, Botté C,…

J. Funct. Foods 2020 64, 103688. doi:10.1016/j.jff.2019.103688

Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration

Broncel M, Dominicus C, Vigetti L, Nofal SD, Bartlett EJ, Touquet B, Hunt A, Wallbank…

Elife 2020 Jul 3;9:e57861

Pyclen-Based Ln(III) Complexes as Highly Luminescent Bioprobes for In Vitro and In Vivo One- and Two-Photon Bioimaging Applications.

Hamon N, Roux A, Beyler M, Mulatier JC, Andraud C, Nguyen C, Maynadier M, Bettache…

J Am Chem Soc. 2020 Jun 3;142(22):10184-10197. doi: 10.1021/jacs.0c03496. Epub 2020 May 21. PMID: 32368907. 2020

Radiation Dose-Enhancement Is a Potent Radiotherapeutic Effect of Rare-Earth Composite Nanoscintillators in Preclinical Models of Glioblastoma

Bulin, A. L., Broekgaarden, M., Chaput, F., Baisamy, V., Garrevoet, J., Busser, B., Brueckner, D.,…

Adv Sci (Weinh) 2020 7, 2001675

Rapid Proteomic Profiling by MALDI-TOF Mass Spectrometry for Better Brain Tumor Classification.

Petre G, Durand H, Pelletier L, Poulenard M, Nugue G, Ray PF, Rendu J, Coutton…

Proteomics Clin Appl 2020

Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage.

Rasmussen, KK., Palencia, A., Varming, AK., El-Wali, H., Boeri Erba, E., Blackledge, M., Hammer, K.,…

PNAS 2020 117(34):20576-20585. doi: 10.1073/pnas.2005218117.

Surface functionalization of gold nanoclusters with arginine: a trade-off between microtumor uptake and radiotherapy enhancement.

Broekgaarden, M., Bulin, A. L., Porret, E., Musnier, B., Chovelon, B., Ravelet, C., Sancey, L.,…

Nanoscale 2020 12, 6959-6963

Systematic genetic and proteomic screens during gametogenesis identify H2BK34 methylation as an evolutionary conserved meiotic mark

Crespo M, et al.

Epigenetics Chromatin 2020 13(1):35

The essential role of intraflagellar transport protein IFT81 in male mice spermiogenesis and fertility.

Qu W, Yuan S, Quan C, Huang Q, Zhou Q, Yap Y, Shi L, Zhang…

Am J Physiol Cell Physiol 2020

The Lid/KDM5 histone demethylase complex activates a critical effector of the oocyte-to-zygote transition

Torres-Campana D#, Kimura S#, Orsi GA, Horard B, Benoit G, Loppin B.

PLoS Genet 2020 Mar 5;16(3):e1008543. doi:10.1371/journal.pgen.1008543

The mechano-sensitive response of β1 integrin promotes SRC-positive late endosome recycling and activation of Yes-associated protein.

Block MR, Brunner M, Ziegelmeyer T, Lallemand D, Pezet M, Chevalier G, Rondé P, Gauthier-Rouviere…

J Biol Chem. 2020 Sep 25;295(39):13474-13487. doi: 10.1074/jbc.RA120.013503. Epub 2020 Jul 19. PMID: 32690605; PMCID: PMC7521633. 2020

The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity.

Lecordier L, Uzureau S, Vanwalleghem G, Deleu M, Crowet JM, Barry P, Moran B, Voorheis…

iScience 2020

Two HIRA- dependent pathways mediate H3.3 de novo deposition and recycling during transcription

Torné J, Ray-Gallet D, Boyarchuk E, Garnier M, Le Baccon P, Coulon A, Orsi GA*, Almouzni…

Nat Struct Mol Biol. 2020 Nov;27(11):1057-1068. doi: 10.1038/s41594-020-0492-7

Using methylome data to inform exposome-health association studies: An application to the identification of environmental drivers of child body mass index

Cadiou S, Bustamante M, Agier L, Andrusaityte S, Basagaña X, Carracedo A, Chatzi L, Grazuleviciene…

Environ Int 2020 May;138:105622

 Aminoacyl-tRNA synthetases as drug targets.

Lukarska, M. & *Palencia, A.

The Enzymes, Elsevier 2020 48:321-350. 10.1016/bs.enz.2020.07.001.