Les publications

Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function.

Dacheux D, Martinez G, Broster Reix C, Beurois J, Lores P, Tounkara M, Dupuy J,…

Elife 2023

The patatin-like phospholipase PfPNPLA2 is involved in the mitochondrial degradation of phosphatidylglycerol during Plasmodium falciparum blood stage development.

Shunmugam S, Quansah N, Flammersfeld A, Islam MM, Sassmannshausen J, Bennink S, Yamaryo-Botté Y, Pradel…

Frontiers in Cellular and Infection Microbiology 2023

Variation in Lipid Species Profiles among Leukemic Cells Significantly Impacts Their Sensitivity to the Drug Targeting of Lipid Metabolism and the Prognosis of AML Patients.

Lo Presti C, Yamaryo-Botté Y, Mondet J, Berthier S, Nutiu D, Botté C, Mossuz P.

International Journal of Molecular Science 2023

3D-Printed Osteoinductive Polymeric Scaffolds with Optimized Architecture to Repair a Sheep Metatarsal Critical-Size Bone Defect

Garot, C. Schoffit, S. Monfoulet, C. Machillot, P. Deroy, C. Roques, S. Vial, J. Vollaire,…

Adv Healthc Mater 2023 The reconstruction of critical-size bone defects in long bones remains a challenge for clinicians. A new osteoinductive medical device is developed here for long bone repair by combining a 3D-printed architectured cylindrical scaffold made of clinical-gra

A Plasmodium falciparum lysophospholipase regulates host fatty acid flux via parasite lipid storage to enable controlled asexual schizogony.

Sheokand PK, Yamaryo-Botté Y, Narwal M, Arnold CS, Thakur V, Islam MM, Banday MM, Asad…

Cell Reports 2023 FRM Press release : https://www.frm.org/recherches-maladies-infectieuses/paludisme/decouverte-de-candidats-medicaments-prometteurs CNRS Press release : https://www.insb.cnrs.fr/fr/cnrsinfo/comment-tuer-le-parasite-de-la-malaria-paludisme-en-le-rendant-ob

Aberrant activation of five embryonic stem cell-specific genes robustly predicts a high risk of relapse in breast cancers

Jacquet E, Chuffart F, Vitte AL, Nika E, Mousseau M, Khochbin S, Rousseaux S, Bourova-Flin…

BMC Genomics 2023 Aug 17;24(1):463. doi: 10.1186/s12864-023-09571-3. PMID: 37592220; PMCID:PMC10436393

Adenosine Dependent Activation Mechanism of Prodrugs Targeting an Aminoacyl-tRNA Synthetase

Hoffmann, G., Le Gorrec, M., Mestdach, E., Cusack, S., Salmon, L., *Jensen, MR. & *Palencia,…

Journal of The American Chemical Society 2023 145(2), 800-810. *Corresponding authors

Bypassing Mendel's First Law: Transmission Ratio Distortion in Mammals.

Friocourt G, Perrin A, Saunders PA, Nikalayevich E, Voisset C, Coutton C, Martinez G, Morel…

Int J Mol Sci. 2023

Coupled mechanical mapping and interference contrast microscopy reveal viscoelastic and adhesion hallmarks of monocyte differentiation into macrophages

Eroles M, Lopez-Alonso J, Ortega A, Boudier T, Gharzeddine K, Lafont F, Franz CM, Millet…

Nanoscale 2023 Jun 28. doi: 10.1039/d3nr00757j.

CRISPR Screens Identify Toxoplasma Genes That Determine Parasite Fitness in Interferon Gamma-Stimulated Human Cells.

Krishnamurthy S, Maru P, Wang Y, Bitew MA, Mukhopadhyay D, Yamaryo-Botté Y, Paredes-Santos TC, Sangaré…

mBio 2023

Cytochalasin D restores nuclear size acting on F-actin and IZUMO1 localization in low-quality spermatozoa.

Martinez G, Cappetta D, Telesca M, Urbanek K, Castaldo G, Dhellemmes M, Mele VG, Chioccarelli…

Int J Biol Sci. 2023

Deficiency of primate-specific SSX1 induced asthenoteratozoospermia in infertile men and cynomolgus monkey and tree shrew models.

Liu C, Si W, Tu C, Tian S, He X, Wang S, Yang X, Yao…

Am J Hum Genet 2023

Developing advanced models of biological membranes with hydrogenous and deuterated natural glycerophospholipid mixtures

Corucci G, Batchu KC, Luchini A, Santamaria A, Frewein MPK, Laux V, Haertlein M, Yamaryo-Botté…

J Colloid Interface Sci 2023 Sep;645:870-881. doi: 10.1016/j.jcis.2023.04.135

Developing advanced models of biological membranes with hydrogenous and deuterated natural glycerophospholipid mixtures.

Corucci G, Batchu KC, Luchini A, Santamaria A, Frewein MPK, Laux V, Haertlein M, Yamaryo-Botté…

Journal of Colloidal and Interface Science 2023

DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice

Yap YT, Li W, Huang Q, Zhou Q, Zhang D, Sheng Y, Mladenovic-Lucas L, Yee…

Elife 2023 Jul 10;26(8):107354. doi:10.7554/eLife.79620.

ERS: A simple scoring system to predict early recurrence after surgical resection for hepatocellular carcinoma

• Costentin C, Audureau E, Park YN, Langella S, Vibert E, Laurent A, Cauchy F,…

Liver Int. 2023 Nov;43(11):2538-2547. doi: 10.1111/liv.15683. Epub 2023 Aug 14. PMID: 37577984.

Expanding the sperm phenotype caused by mutations in SPATA20: A novel splicing mutation in an infertile patient with partial globozoospermia.

Martinez G, Metzler-Guillemain C, Cazin C, Kherraf ZE, Paulmyer-Lacroix O, Arnoult C, Ray PF, Coutton…

Clin Genet. 2023

Force tuning through regulation of clathrin-dependent integrin endocytosis.

Kyumurkov A, Bouin AP, Boissan M, Manet S, Baschieri F, Proponnet-Guerault M, Balland M, Destaing…

JCB 2023 Jan 2;222(1):e202004025.doi: 10.1083/jcb.202004025. Epub 2022 Oct 17.

Genetic causes of macrozoospermia and proposal for an optimized genetic diagnosis strategy based on sperm parameters.

Coudert A, Cazin C, Amiri-Yekta A, Fourati Ben Mustapha S, Zouari R, Bessonat J, Zoghmar…

J Genet Genomics. 2023

High levels of histone H3 K27 acetylation and tri-methylation are associated with shorter survival in oral squamous cell carcinoma patients

Shahhosseini A, Bourova-Flin E, Derakhshan S, Aminishakib P, Goudarzi A.

Biomedicine (Taipei) 2023 Mar 1;13(1):22-38. doi: 10.37796/2211-8039.1391. PMID: 37168723; PMCID:PMC10166250

Identification of IQCH as a calmodulin-associated protein required for sperm motility in humans

Cavarocchi E, Sayou C, Lorès P, Cazin C, Stouvenel L, El Khouri E, Coutton C,…

iScience 2023 Jul 10;26(8):107354. doi:10.1016/j.isci.2023.107354.

Identification of IQCH as a calmodulin-associated protein required for sperm motility in humans.

Cavarocchi E, Sayou C, Lorès P, Cazin C, Stouvenel L, El Khouri E, Coutton C,…

iScience 2023

Maternal imprinting and determinants of neonates' immune function in the SEPAGES mother-child cohort

Manches O, Um K, Boudier A, Maddouri Y, Lyon-Caen S, Bayat S, Slama R, Philippat…

Front Immunol. 2023 Apr 4;14:1136749. doi: 10.3389/fimmu.2023.1136749. PMID: 37081891; PMCID: PMC10111372.

New Mutations in DNHD1 Cause Multiple Morphological Abnormalities of the Sperm Flagella.

Martinez G, Barbotin AL, Cazin C, Wehbe Z, Boursier A, Amiri-Yekta A, Daneshipour A, Hosseini…

Int J Mol Sci 2023

NIR-II Aza-BODIPY Dyes Bioconjugated to Monoclonal Antibody Trastuzumab for Selective Imaging of HER2-Positive Ovarian Cancer.

Godard, A., Kalot, G., Privat, M., Bendellaa, M., Busser, B., Wegner, K. D., Denat, F.,…

J Med Chem 2023 Using fluorescence-guided surgery (FGS) to cytoreductive surgery helps achieving complete resection of microscopic ovarian tumors. The use of visible and NIR-I fluorophores has led to beneficial results in clinical trials; however, involving NIR-II dyes s

Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function.

Dacheux D, Martinez G, Broster Reix C, Beurois J, Lores P, Tounkara M, Dupuy J,…

Elife 2023

Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet

• Iuso D, Garcia-Saez I, Couté Y, Yamaryo-Botté Y, Boeri Erba E, Adrait A, Zeaiter…

Science Advances 2023 Sep 8;9(36):eadh0140. doi: 10.1126/sciadv.adh0140. Epub 2023 Sep 6. PMID: 37672589; PMCID: PMC10482350.

Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet.

Iuso D, Garcia-Saez I, Couté Y, Yamaryo-Botté Y, Boeri Erba E, Adrait A, Zeaiter N,…

Science Advances 2023

OTX2 duplications: a recurrent cause of oculo-auriculo-vertebral spectrum.

Celse T, Tingaud-Sequeira A, Dieterich K, Siegfried G, Lecaignec C, Bouneau L, Fannemel M, Salaun…

J Med Genet. 2023

Protocol to study the role of a human nuclear m6A RNA reader on chromatin-associated RNA targets

Seigneurin-Berny D, Touat-Todeschini L, Timcheva K, Verdel A

STAR Protocols 2023

Results and perinatal outcomes from 189 ICSI cycles of couples with asthenozoospermic men and flagellar defects assessed by transmission electron microscopy.

Boursier A, Boudry A, Mitchell V, Loyens A, Rives N, Moerman A, Thomas L, Escudier…

Reprod Biomed Online 2023

Sperm Meiotic Segregation Analysis of Reciprocal Translocations Carriers: We Have Bigger FISH to Fry.

Del Llano E, Perrin A, Morel F, Devillard F, Harbuz R, Satre V, Amblard F,…

Int J Mol Sci 2023

The fate of mitochondria during platelet activation.

Grichine A, Jacob SP, Eckly AE, Villaret J, Joubert C, Appaix F, Pezet M, Ribba…

Blood Adv. 2023 Oct 24;7(20):6290-6302. doi: 10.1182/bloodadvances.2023010423. PMID: 37624769; PMCID: PMC10589785. 2023

The SMYD3-MAP3K2 signaling axis promotes tumor aggressiveness and metastasis in prostate cancer

Sabeen Ikram, Apurv Rege, Maraki Y Negesse, Alexandre G Casanova, Nicolas Reynoird, Erin M Green

Science Advances 2023

Understanding the genetics of human infertility.

Sang Q, Ray PF, Wang L.

Science 2023