Les publications

Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis

A Casanova, G Roth, S Hausmann, X Lu, L Bischoff, E Froeliger, L Belmudes, E…

Cell Discovery 2024

Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis.

Casanova, AG., Roth, GS., Hausmann, S., Lu, X., Bischoff, LJM., Froeliger, EM., ... Rousseaux, S.,…

Cell Discovery 2024 10(1):12. doi: 10.1038/s41421-023-00644-x.

Development of a New Off-the-Shelf Plasmacytoid Dendritic Cell–Based Approach for the Expansion and Characterization of SARS-CoV-2–Specific T Cells

Maino A, Amen A, Plumas J, Bouquet L, Deschamps M, Saas P, Chaperot L, Manches…

J Immunol. 2024 Jan 12:ji2300704. doi: 10.4049/jimmunol.2300704. Epub ahead of print. PMID: 38214610.

Engineering Radiocatalytic Nanoliposomes with Hydrophobic Gold Nanoclusters for Radiotherapy Enhancement

Carigga Gutierrez, N. M. Clainche, T. L. Bulin, A. L. Leo, S. Kadri, M. Abdelhamid,…

Adv Mater 2024 Chemoradiation therapy is on the forefront of pancreatic cancer care, and there is a continued effort to improve its safety and efficacy. Liposomes are widely used to improve chemotherapy safety, and may accurately deliver high-Z element- radiocatalytic n

Enhanced CRISPR-Cas9 RNA system delivery using cell penetrating peptides-based nanoparticles for efficient in vitro and in vivo applications

Guzman Gonzalez, V. Grunenberger, A. Nicoud, O. Czuba, E. Vollaire, J. Josserand, V. Le Guevel,…

J Control Release 2024 CRISPR-Cas9 system has emerged as a revolutionary gene-editing tool with huge therapeutic potential for addressing the underlying genetic causes of various diseases, including cancer. However, there are challenges such as the delivery method that must be

In vitro production of cat-restricted Toxoplasma pre-sexual stages

Ana Vera Antunes, Martina Shahinas, Christopher Swale, Dayana C. Farhat, Chandra Ramakrishnan, Christophe Bruley, Dominique…

Nature 2024 These authors contributed equally: Ana Vera Antunes, Martina Shahinas, Christopher Swale

Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers

Khaldoun Gharzeddine, Cristina Gonzales Pietro, Marie Malier, Clara Hennot, Renata Grespan, Yoshiki Yamaryo-Botté, Cyrille Y.…

BioRxiv 2024

Methylation of ESCRT-III components regulates the timing of cytokinetic abscission

Richard A, Berthelet J, Judith D, Advedissian T, Espadas J, Jannot G, Amo A, Loew…

Nat Commun. 2024

Nanoscintillator Coating: A Key Parameter That Strongly Impacts Internalization, Biocompatibility, and Therapeutic Efficacy in Pancreatic Cancer Models

Aubrun Fulbert, Clémentine Chaput, Frédéric Stelse‐Masson, Sarah Henry, Maxime Chovelon, Benoit Bohic, Sylvain Brueckner, Dennis…

Small Science 2024 Pancreatic cancer is associated with a poor prognosis despite multimodal treatments. To improve the efficacy of radiotherapy, the use of nanoscintillators is emerging. Made of high-Z elements, they absorb X-rays more efficiently than tissues and can local

PD1 and TIM3 Expression is Associated with Very Early Hepatocellular Carcinoma Recurrence After Percutaneous Thermal Ablation

Ghelfi J, Macek Jilkova Z , Sengel C, Brusset B, Teyssier Y, Costentin C, Mercey-Ressejac…

Journal of Hepatocellular Carcinoma. 2024 https://doi.org/10.2147/JHC.S443134

Phage display identification of high-affinity ligands for human TSG101-UEV: A structural and thermodynamic study of PTAP recognition.

Murciano-Calles, J., Rodríguez-Martínez, A., Palencia, A., Andújar-Sánchez, M., Iglesias-Bexiga, M., Corbi-Verge, C., Buzón, P., Ruiz-Sanz,…

Int J Biol Macromol. 2024 274(1):133233, 10.1016.

Quantifying Titanium Exposure in Lung Tissues: A Novel Laser‐Induced Breakdown Spectroscopy Elemental Imaging‐Based Analytical Framework for Biomedical Application

Gardette, V. Sancey, L. Leprince, M. Gaté, L. Cosnier, F. Seidel, C. Valentino, S. Pelascini,…

Small Science 2024 Occupational and environmental exposures, particularly those related to urban and suburban atmospheres, are increasingly linked to a range of pulmonary diseases. While diagnostic methods for these diseases are well established, analytical tools for assess

Self-assembled peptide-gold nanoclusters with siRNA targeting telomeric response to enhance radiosensitivity in lung cancer cells.

Moro, S. Omrani, M. Erbek, S. Jourdan, M. Vandekerckhove, V. I. Nogier, C. Vanwonterghem, L…

Small Science 2024 Lung cancer cells resistant to radiotherapy present a significant clinical challenge. Stable telomeric structures, maintained by the TRF2 protein, play a critical role in protecting cells from ionizing radiation. Reduced TRF2 expression increases DNA dama

Serum IGF1 Is a Prognostic Marker for Resistance to Targeted Therapies and a Predictive Marker for Anti-IGF1 Receptor Therapy in Melanoma

Castillo-Ferrer, C. Marguet, T. Vanwonterghem, L. Erbek, S. Chuffart, F. Mouret, S. Messai, S. T.…

J Invest Dermatol 2024 Institute for Advanced Biosciences, INSERM U1209, CNRS UMR5309, Grenoble Alpes University, Grenoble, France; Ecole Pratique des Hautes Etudes, PSL Research University, Paris, France. Institute for Advanced Biosciences, INSERM U1209, CNRS UMR5309, Grenobl

Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1

Mariño Pérez, L., Ielasi, FS., Lee, A., Delaforge, E., Juyoux, P., Tengo, M., Davis, RJ.,…

Structure 2024 S0969-2126(24)00228-4. doi: 10.1016/j.str.2024.06.010

Targeting a microbiota Wolbachian aminoacyl-tRNA synthetase to block its pathogenic host.

Hoffmann, G., Lukarska, M., Clare, RH., Masters, EKG., Johnston, KL., Ford, L., Turner, JD., Ward,…

Science Advances 2024 10(28):eado1453. doi: 10.1126/sciadv.ado1453.