Les publications

A homozygous ancestral SVA-insertion mediated deletion in WDR66 induces multiple morphological abnormalities of the sperm flagellum and male infertility

Kherraf Z.E., Amiri-Yekta A., …, Arnoult C., Bonhivers M. and Ray P.F.

American Journal of Human genetics 2018 103(3):400-412. doi: 10.1016/j.ajhg.2018.07.014 IF 10.36

Absence of cilia- and flagella-associated protein 69 (CFAP69) causes male infertility due to multiple morphological abnormalities of the flagella (MMAF) in human and mouse

Dong F.N., Amiri-Yekta A., …. Arnoult C., Touré A. , Ray P.F., Zhao H., Coutton…

American Journal of Human genetics 2018 102: 636-648. doi: 10.1016/j.ajhg.2018.03.007 IF IF 8.85

Anti-tumor efficacy of hyaluronan-based nanoparticles for the co-delivery of drugs in lung cancer

Jeannot, V., Gauche, C., Mazzaferro, S., Couvet, M., Vanwonterghem, L., Henry, M., Didier, C., Vollaire,…

J Control Release 2018 275, 117-128

BET Family Protein BRD4: An Emerging Actor in NFκB Signaling in Inflammation and Cancer

Hajmirza A, et al. 

Biomedicines 2018 6(1)

Characterization of a Toxoplasma effector uncovers an alternative GSK3/b-catenin-regulatory pathway of inflammation.

He H, Brenier-pinchart MP, Braun L, Kraut A, Touquet B, Coute Y, Tardieux I, Hakimi…

Elife 2018 Oct 15;7. pii: e39887

Characterization of foreign materials in paraffin-embedded pathological specimens using in situ multi-elemental imaging with laser spectroscopy

Busser, B., Moncayo, S., Trichard, F., Bonneterre, V., Pinel, N., Pelascini, F., Dugourd, P., Coll,…

Mod Pathol 2018 31, 378-384

Deciphering the Dynamic Interaction Profile of an Intrinsically Disordered Protein by NMR Exchange Spectroscopy.

Delaforge, E., Kragelj, J., Tengo, L., Palencia, A., Milles, S., Bouvignies, G., Salvi, N., Blackledge,…

Journal of The American Chemical Society 2018 140(3):1148-1158. doi: 10.1021/jacs.7b12407.

Heteromultivalent targeting of integrin alphavbeta3 and neuropilin 1 promotes cell survival via the activation of the IGF-1/insulin receptors

Jia, T., Choi, J., Ciccione, J., Henry, M., Mehdi, A., Martinez, J., Eymin, B., Subra,…

Biomaterial 2018 155, 64-79

Heteromultivalent targeting of integrin avb3 and neuropilin 1 promotes cell survival via the activation of the IGF-1/insulin receptors

Jia T, Choi J, Ciccione J, Henry M, Mehdi A, Martinez J, Eymin B, Subra…

Biomaterials 2018 155:64-79 doi: 10.1016/j.biomaterials.2017.10.042

High-resolution visualization of H3 variants during replication reveals their controlled recycling

Clément C, Orsi GA, Gatto A, Boyarchuk E, Forest A, Hajj B, Miné-Hattab J, Garnier M,…

Nat Commun 2018 Aug 9;9(1):3181. doi:10.1038/s41467-018-05697-1

Imaging Newly Synthesized and Old Histone Variant Dynamics Dependent on Chaperones Using the SNAP-Tag System

Torné J, Orsi GA, Ray-Gallet D, Almouzni G.

Methods Mol Biol 2018 1832:207-221. doi: 10.1007/978-1-4939-8663-7_11. PMID: 30073529.

Kinetic origin of substrate specificity in post-transfer editing by leucyl-tRNA synthetase.

Dulic, M., Cvetesic, N., Zivkovic, I., Palencia, A., Cusack, S., Bertosa, B. & Gruic-Sovulj, I.

Journal of Molecular Biology 2018 430(1):1-16. doi: 10.1016/j.jmb.2017.10.024.

Lysine methylation signaling in pancreatic cancer

Roth GS, Casanova AG, Lemonnier N, Reynoird N.

Curr Opin Oncol. 2018 2018 Jan;30(1):30-37. doi: 10.1097/CCO.0000000000000421. PMID: 29076964

Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human

Coutton C, Vargas AS, …., Arnoult C, Ray PF.

Nature Comm 2018 9: 686-96. doi: 10.1038/s41467-017-02792-7* co dernier auteur IF 12.12

Nuclear translocation of IGF-1R by intracellular amphiregulin contributes to the resistance of lung tumor cells to EGFR-TKI

Guerard M, Robin T, Perron P, Hatat A.S, David-Boudet L, Busser B, Coll J.L, Lantuejoul…

Cancer Letters 2018 420:146-155 doi: 10.1016/j.canlet.2018.01.080

Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells

Shiota H, Barral S, Buchou T, Tan M, Couté Y, Charbonnier G, Reynoird N, Boussouar…

Cell Report 2018 Sep 25;24(13):3477-3487.e6. doi: 10.1016/j.celrep.2018.08.069. PMID: 30257209

Nut Directs p300-Dependent, Genome-Wide H4 Hyperacetylation in Male Germ Cells

Shiota H, Barral S, Buchou T, Tan M, Couté Y, Charbonnier G, Reynoird N, Boussouar…

Cell Rep 2018 24:3477-3487.e6.

PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice

Christou-Kent M. , Zine-Eddine Kherraf Z-E, …. and Arnoult C.

EMBO Molecular Medicine 2018 10(5). pii: e8515. doi: 10.15252/emmm.201708515 IF 9.50

Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse

El Khouri E, Whitfield M, Stouvenel L, Kini A, Riederer B, Lores P,Roemermann D, di…

Mol Reprod Dev 2018 Aug;85(8-9):682-695.

Systematic quantitative analysis of H2A and H2B variants by targeted proteomics

El Kennani S, et al. 

Epigenetics Chromatin 2018 11(1):2

The sVEGFR1-il3 splice variant regulates a beta1 integrin/VEGFR autocrine loop involved in the progression and the responce to anti-angiogenic therapies of squamous cell lung carcinoma

Abou Faycal C, Brambilla E, Agorreta J, Lepeltier N, Jacquet T, Lemaitre N, Emadali A,…

British Journal of Cancer 2018 118 :1596-1608 doi: 10.1038/s41416-018-0128-4. 

Toxoplasma Parasite Twisting Motion Mechanically Induces Host Cell Membrane Fission to Complete Invasion within a Protective Vacuole

Pavlou G, Biesaga M, Touquet B, Lagal V, Balland M, Dufour A, Hakimi MA, Tardieux…

Cell Host Microbe 2018 Jul 11;24(1):81-96.e5

Transcription factor dimerization activates the p300 acetyltransferase

Ortega E, Rengachari S, Ibrahim Z, Hoghoughi N, Gaucher J, Holehouse AS, Khochbin S, Panne D.

Nature 2018 562: 538-544

Whole-exome sequencing identifies mutations in the Fibrous Sheath Interaction Protein 2 (FSIP2) as a recurrent cause of multiple morphological abnormalities of the sperm flagella (MMAF)

Martinez G., Raoudha Zouari R., …., Arnoult C., Ray P.F., Coutton C.

Human reproduction 2018 33(10):1973-1984. doi: 10.1093/humrep/dey264 IF 5.00